Plastic pollution is a pressing global problem, even in Antarctica and the Southern Ocean, despite their remote and pristine nature. Coming from local sources but also from lower latitudes, the consequences of this pollution, especially of microplastics in Antarctica, are far from being known. The growing evidence of this environmental problem and the growing concern of the Antarctic community has led to a significant increase in research and monitoring initiatives, such as the AntarPLAST Project. While several challenges have been identified for the assessment regarding monitoring and managing plastic and microplastic pollution, possible ways to address them in a collaborative, coordinated, and equitable manner are also envisioned under the newly Antarctic InSync proposal.